Antimalarial Phytochemicals Identification from Euphorbia Hirta against Plasmepsin Protease: an In Silico Approach
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چکیده
منابع مشابه
Potential Applications of Euphorbia hirta in Pharmacology
Euphorbia is a genus of plants belonging to the family Euphorbiaceae. Botanist and taxonomist Carl Linnaeus assigned the name Euphorbia to the entire genus in the physician's honor. Euphorbia hirta is a very popular herb amongst practitioners of traditional herb medicine, widely used as a decoction or infusion to treat various ailments including intestinal parasites, diarrhoea, peptic ulcers, h...
متن کاملGenotoxicity of Euphorbia hirta: an Allium cepa assay.
The potential genotoxic effects of methanolic extracts of Euphorbia hirta which is commonly used in traditional medicine to treat a variety of diseased conditions including asthma, coughs, diarrhea and dysentery was investigated using Allium cepa assay. The extracts of 125, 250, 500 and 1,000 µg/mL were tested on root meristems of A. cepa. Ethylmethanesulfonate was used as positive control and ...
متن کاملPartial Purification of Cytotoxic Peptides against Gastric Cancer Cells from Protein Hydrolysate of Euphorbia hirta Linn
Protein hydrolysates prepared from a number of medicinal plants are promising sources of various bioactive peptides. In this work, proteins from dried whole plant of Euphorbia hirta Linn. were extracted and digested with pepsin for 12h. The hydrolysates of lesser than 3 KDa were fractionated by a cut-off membrane. The peptide hydrolysate was then purified by an anionexchange chromatography on D...
متن کاملBURN WOUND HEALING ACTIVITY OF Euphorbia hirta
The Ethanolic extract of whole plant of Euphorbia hirta was screened for burn wound healing activity in rats as 2% W/W cream. The study was carried out based on the assessment of percentage reduction in original wound. It showed significant burn wound healing activity.
متن کاملMicrosciadin, a New Milk-Clotting Cysteine Protease from an Endemic Species, Euphorbia microsciadia
In the present work, a new branch of biotechnological advantage of the latex of an endemic perennial plant, Euphorbia microsciadia has been introduced. A novel cysteine protease, designated as microsciadin, was purified from the latex of Euphorbia microsciadia by a combination of sequential usage of SP-Sepharose Fast Flow column in two different pHs and a final gel filtration ...
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ژورنال
عنوان ژورنال: Folia Medica
سال: 2019
ISSN: 1314-2143,0204-8043
DOI: 10.3897/folmed.61.e47965